Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

On April 24, Zhou took the pesticide to the Yimin Technician Training School in Rongchang, Chongqing and hid the toxic substance under a desk.
Demagogues are the Achilles heel of democracy.
Anxiety about addiction to screen time gave rise to a dubious new line of businesses: boot camps, often run by ex-military personnel, promising to help wayward youth kick the habit. But investigative reports p ublished in recent days by Beijing News and the Mirror reveal abusive conditions, leading to the death of at least one student, at the Zhengzhou Boqiang New Idea Life Training School, which billed itself a s an Internet-addiction recovery camp in eastern Henan province.
Which brands most improved their reputations in social media in 2012? And which companies made them worse?
迪皮卡 帕度柯妮
n. 失业,失业人数
这个触动人心的成长故事完美捕捉了一个人从青少年初长为成年人的甜蜜又苦涩的阶段。
要让产品显得很“酷”并不是唯一的目的。科技行业如果想让我们身体的更多部位连上网络,那么安全问题和隐私问题,尤其是顾客数据管理问题,依旧需要慎重考虑。正如《经济学人》(The Economist)所说,蓬勃发展的传感器的魅力,以及可穿戴设备的算法,分散了人们对于其他要素的关注。这些关键的其它要素包括:“标准、互通性、一体化、数据管理”,以及“知识产权、执行标准”。对国家安全局(National Security Administration)而言,这些技术发展都必须以网络安全为前提。
The need to rebuild supersedes the desire to not give Boston another great pick. That hole has already been dug. Time to crawl out the only way you can: slowly, through smart draft picks, trades, and signings.
n. 繁荣,兴旺
This is the second year running that Peking University has reached the height of No. 2 university.
The top obsession of 2010 was the much-anticipated iPhone, followed by actress Lindsay Lohan, the iPad, and the television shows "Glee" and "Jersey Shore".
越南声称来自中国的鸡肉、鲟鱼和果蔬降低了当地产品的市场价位,而他们却将严重过期的不法产品运至中国,甚至还形成了黑市。
setting
Yan Pu, head of portfolio review in Asia at Vanguard, suspects the Asian product mix may be holding things back. For example, Asian providers offer plenty of equity ETFs but very few fixed income products. In the US, she notes, fixed income ETFs are growing rapidly.
5.X-Men: Apocalypse
今年夏季,美国ETF管理的资产规模跨过3万亿美元大关,亚太ETF行业管理的资产仅成功爬上3500亿美元关口。
She also said that in the longer-term the other “R” was “reset”, by which she explained that monetary and fiscal policies around the world still had a long way to go before they could be classed as normal. “The final reset is those structural reforms that are necessary in all corners of the world,” she added.
vt. 安慰,使
“The key thing about Friends is that it’s about people working out how they are going to live their lives — what kind of relationships are they going to have, what kind of job, and the difficulties of settling down,” says Mills to the Daily Mail. “You’re engaged in all those questions about escaping from your family, becoming an adult and working out what you want to be.”And that’s one of the key issues in the youth culture of the 1990s.
May you have the best New Year ever.愿你度过最美好的新年!
In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.
评审委员会(就我一人)花了几周的时间来决定王室、政界以及明星当中谁应该获得一枚令人难堪的奖章,以表彰他们过去一年严重违反礼仪或行为失态的表现。
St. Vincent “Digital Witness” (Loma Vista/Republic)
市场观察人士被迫接受一季度美国GDP负增长2.9%这一现实。突然间,同波诡云谲的现实相比,所有人的预测似乎都过于乐观,至少是过于平稳。这导致人们纷纷猜测美联储最终退出其债券购买计划的时机。短短几周内,我们从信心满满变成了垂头丧气,同时,伴随着不确定性的再次来袭,资产类别的交替以及市场调整也随之而来。


n. 非法移民
Challenger说:“工作总会有的。公司总是在招聘,只是竞争更加残酷了。”
这部亚当·桑德勒和德鲁·巴里摩尔主演的轻松浪漫喜剧,似乎最不能反映现实生活,但实际上它确实部分基于真实故事。桑德勒扮演的兽医爱上了巴里摩尔,而她的记忆每天都会重置。他了解到,车祸造成创伤性脑损伤后,她就一直在重播同一天。因为她一直生活在谎言中,桑德勒的角色很苦恼,并制作了一系列录像,解释她的车祸和生活,给她每天早上看。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

trademark
Summly was backed by Horizons Ventures, the venture capital arm of Hong Kong billionaire Li Ka-shing, and other tech and media names including actors Ashton Kutcher and Stephen Fry, Spotify’s Shakil Khan and Zynga’s Mark Pincus .
但关于是否会诞生另一个火爆产品,来打破关于后乔布斯时代苹果前途的质疑,库克许久以前就学会了耐心和相信自己的直觉,正如他在1998年加入正处在困境中的苹果时对质疑者置之不理一样。
眼见克莱斯勒的市场份额呈现死亡式螺旋下降,菲亚特会最终认识到这个不中用的公司还真就是不中用了。预计菲亚特会在8月前扬言彻底和克莱斯勒分道扬镳,除非全美汽车工人联合会(UAW)和美国纳税人作出更多让步。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

Summly对这一难题的解决方式是创建文章的“快照”,比起阅读整篇文章,该功能可提高读者的浏览速度。尽管应用将关闭,但达洛伊西奥的技术将整合进雅虎的移动应用。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Horowitz admitted that while doing so he has had to work carefully to preserve 007's characters and attitude as created by the spy novel’s first author Ian Fleming, who died in 1964.
单词prosperity 联想记忆:

Average years of work experience: 11
The GDP of Southwest China's Chongqing Municipality grew by 10.7 percent in 2016, hitting 1.76 trillion yuan. Southwest China's Guizhou province and Tibet autonomous region posted 10.5 percent and 10 percent growth respectively.
Manufacturer of advanced and quality products
We will make big moves to improve the environment for foreign investors.
本文为与《创业者》杂志的合作内容。下文最初发表于Entrepreneur.com。
2. Tell all your friends not to give birth or wed or die or whatever during the World Cup coz we won’t go.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


北京公租房小区标配“人脸识别”


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


It is not unusual for the documented wealth of China’s richest people to surge suddenly — or even for previously unknown tycoons to burst into prominence — as stock exchange listings and other public investments thrust them into the spotlight.
Detectives have laid charges, but said they will not release the details of the offenses until Friday when both the 18-year-old and the youth are expected to appear in court.
[in'tendid]
reservation
“…claimed he was late because he got lost, but our receptionist said she had seen him hanging out at the coffee shop.”
v
年度故事将是纽约对911主谋穆罕默德(Khalid Sheikh Mohammed)的审判。
5.Effective decision makers
After weeks of rumors, Phil Jackson failed to move Carmelo Anthony and Derrick Rose, two players who absolutely should have been traded for the long-term benefit of the franchise.
The booming Internet economy now is playing an increasingly important role in supporting wealth growth in China's IT industry.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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In 2013, the total number of applicants who qualified for the national service exam reached a record 1.52 million. In 2014, the total number decreased for the first time in four years to 1.41 million, the People's Daily website said.
发脾气大奖
NPLs rose from 1.25 per cent of total loans to 1.67 per cent by the end of 2015, amounting to Rmb1.27tn held by commercial banks.
年龄:56岁

其中涉嫌售假的占比近45%,同比去年上升18.2%。消费者差评、频繁退货、投诉案例也很多。部分商家通过虚假低价的商业陷阱来促销商品。

  • Only the first three authors are listed, followed by "et al."
  • 防水壁纸横空出世 传统材料或将淘汰
  • 各地楼市成交量冷热不均 二元分化格局或将加剧


卡恩称,Summly的机器学习和自然语言处理能力背后的设想和技术“均很出色”。
Profits fell by 54 per cent year-on-year to Rmb105.6bn ($15.9bn) during the period, a drop of Rmb124.4bn, according to figures published by the China Insurance Regulatory Commission.

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